You don't say what kind of design it is, which might make a difference.
There's sort of an escalating scale of bigger and bigger character sets one can consider, for language coverage. Semi-independently are some questions of typographic coverage.
At Adobe, our most basic character set is essentially the union of MacRoman and WinANSI (codepage 1252), plus litre and estimated.
Some typographic things one might consider as "relatively" standard, depending on the design:
- having all five f-ligatures (fi fl ff ffi ffl)
- more fractions, or a full set of numeric numerators/denominators/superiors/inferiors
- small caps
For the next step in language coverage, we do "Adobe CE" which includes Windows Eastern European, Baltic and Turkish codepages.
See also http://www.adobe.com/type/browser/info/charsets.html
It keeps on escalating after that, but you probably don't want to have 3000 glyphs per font. :/
Cheers,
T